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Calcium hydroxyapatite microspheres (CaHA) are widely used in aesthetic medicine for facial soft-tissue filling and contour shaping. With a 25–45 μm microsphere structure, they provide immediate support while stimulating collagen formation, delivering both structural support and tissue-regeneration effects.
As an important inorganic component of human hard tissue, hydroxyapatite offers excellent biocompatibility and osteoconductivity. It is widely used in bone-defect filling, artificial bone granules, bone-repair scaffolds, bone-cement composites, and 3D-printed bone substitute structures, providing a stable inorganic framework for bone regeneration.
Hydroxyapatite can be deposited onto titanium and titanium-alloy implant surfaces through plasma spraying and related techniques to form bioactive coatings. This significantly improves bonding between the implant and bone tissue, accelerates osseointegration, and is widely used in orthopedic and dental implant systems.
In oral medicine, hydroxyapatite is commonly used in clinical scenarios such as alveolar-bone defect repair, periodontal bone regeneration, extraction-socket preservation, sinus lifting, and peri-implant bone augmentation, making it one of the important bone-substitute materials in dentistry.